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A region of the brain that monitors and coordinates aspects of the internal environment, including body temperature.

A region of the brain that produces TRH as part of the control of thyroxine levels.

The body needs enough thyroxine to support an appropriate metabolic rate, but the concentration must also be controlled. It does this through a chain involving three parts of the endocrine system: the hypothalamus, the pituitary gland and the thyroid gland.

A region of the brain that monitors the temperature of the blood and coordinates responses to changes in body temperature.

For a sequence question, name each structure as well as each hormone: hypothalamus → TRH → pituitary gland → TSH → thyroid gland → thyroxine.

Keep the hypothalamus and pituitary distinct: the hypothalamus regulates internal conditions and controls the pituitary; the pituitary releases many hormones.

Build explanations as a pathway: temperature change → receptor → hypothalamus → nerve impulses → effectors → corrective responses.

A brain region that helps regulate internal conditions, including body temperature, and controls hormone release from the pituitary gland.

The hypothalamus is a small region beneath the cerebrum. It helps maintain stable conditions inside the body, a process called homeostasis. One important example is the regulation of body temperature.

Thermoreceptors in the hypothalamus monitor the temperature of the blood flowing through the brain, providing information about internal temperature.

A region of the brain that contains osmoreceptors, processes information about blood concentration and controls the pituitary gland’s release of ADH.

Hypothalamus

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Edexcel GCSE Biology · 1BI0

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OCR GCSE Biology A · J247

OCR GCSE Biology B · J257