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GCSE Combined Science · key term
A disorder in which the pancreas produces insufficient insulin, causing uncontrolled high blood glucose levels unless treated.
Used by AQA and Edexcel
Specification 4.5.3.2 · Paper 2
Revise: Blood Glucose ControlIn Type 1 diabetes, the pancreas fails to produce sufficient insulin. This usually happens because the immune system destroys insulin-producing cells in the pancreas. Without enough insulin, glucose uptake and storage are not stimulated adequately, so glucose remains in the blood.
Paper 1, Paper 2
A disorder in which the pancreas produces little or no insulin because the immune system destroys insulin-producing cells.
Revise: Homeostasis and Blood GlucoseIn type 1 diabetes, the immune system attacks and destroys the insulin-producing cells of the pancreas. The pancreas consequently produces little or no insulin.
Type 1 diabetes involves insufficient insulin production; type 2 involves reduced responsiveness to insulin, often alongside insufficient insulin production.
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