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Edexcel GCSE Biology · 1BI0
Edexcel 1BI0 · 5.5 Common Infections Check the specification (PDF) (opens in a new tab)
A pathogen is an organism that causes disease. Bacteria are single-celled microorganisms, but only some are pathogenic. Pathogenic bacteria may multiply in the body and damage tissues; some also produce toxins that harm cells.
This lesson compares three bacterial infections. For each one, keep a clear chain in mind:
infection → type of pathogen → main effect
Cholera is caused by bacteria. Its characteristic symptom is diarrhoea, meaning the frequent passing of loose or watery faeces.
The important association is:
cholera → bacterium → diarrhoea
Diarrhoea is the effect of the infection, not the pathogen itself. Severe diarrhoea also means that the body loses water, although the required identifying symptom here is diarrhoea.
Tuberculosis, usually shortened to TB, is also caused by bacteria. TB damages lung tissue, so its specified effect is lung damage. Coughing may occur, but the key association required for this infection is:
tuberculosis → bacterium → lung damage
This distinguishes the disease from cholera: both are bacterial, but they affect different parts of the body and cause different effects.
Bacteria called Helicobacter, commonly Helicobacter pylori, can cause stomach ulcers. An ulcer is a break or sore in the lining of an organ. Here, the bacterium is the pathogen and the stomach ulcer is the resulting damage.
The association is:
Helicobacter bacterium → damage to the stomach lining → stomach ulcer
Do not reverse this relationship: a stomach ulcer is not a microorganism and therefore is not the pathogen.
All three examples involve bacterial pathogens, but their effects differ:
| Infection or pathogen | Pathogen type | Main effect |
|---|---|---|
| Cholera | Bacterium | Diarrhoea |
| Tuberculosis (TB) | Bacterium | Lung damage |
| Helicobacter |
A useful way to answer a description question is to state the complete biological link. For example: “Tuberculosis is a bacterial infection that causes lung damage.”
The bacterium is the pathogen; diarrhoea, lung damage and stomach ulcers are effects of infection.
All three examples are bacterial, but they affect different body systems: cholera is associated with the gut, TB with the lungs, and Helicobacter with the stomach lining.
Link each infection to both its pathogen type and its stated effect: cholera — bacteria — diarrhoea; tuberculosis — bacteria — lung damage; Helicobacter — bacteria — stomach ulcers.
Do not describe a stomach ulcer itself as a pathogen. The pathogen is a Helicobacter bacterium; the ulcer is damage associated with the infection.
Use the full term “tuberculosis” before abbreviating it to “TB”.
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Last updated
Pathogen
A disease-causing organism.
Bacterium
A type of single-celled microorganism; some bacteria are pathogens that cause disease.
Cholera
A bacterial disease that causes diarrhoea.
Tuberculosis (TB)
A bacterial disease that damages the lungs.
Helicobacter
A genus of bacteria associated with stomach ulcers; the relevant species is commonly called Helicobacter pylori.
Diarrhoea
Frequent passing of loose or watery faeces.
Ulcer
A break or sore in the lining of an organ, such as the stomach.
Put your knowledge into practice — try past paper questions for Biology
Pathogen
A disease-causing organism.
Bacterium
A type of single-celled microorganism; some bacteria are pathogens that cause disease.
Cholera
A bacterial disease that causes diarrhoea.
Tuberculosis (TB)
A bacterial disease that damages the lungs.
Helicobacter
A genus of bacteria associated with stomach ulcers; the relevant species is commonly called Helicobacter pylori.
Diarrhoea
Frequent passing of loose or watery faeces.
Ulcer
A break or sore in the lining of an organ, such as the stomach.
| Bacterium |
| Stomach ulcers |